Timothy Ray Brown is the only human ever cured of HIV. He had the virus for
11 years before developing leukemia. When he was given a bone marrow
transplant, the HIV virus disappeared. His blood has been studies for years but
there’s still no definitive answer as to why he recovered.
British man might be first in the world to be cured of HIV,Only One Person In History Has Ever Been Cured Of HIV,How the man cured of AIDS has inspired doctors to discover,Who was the first person infected with HIV and how were they infected,science news,medical news
Timothy Ray Brown (1966) is an American boy considered to be the first person cured of HIV/AIDS.Brown was diagnosed with HIV in 1995 while studying in Berlin, Germany.they give him the nickname The Berlin Patient.
Timothy Ray Brown-tech columnist |
British man might be first in the world to be cured of HIV,Only One Person In History Has Ever Been Cured Of HIV,How the man cured of AIDS has inspired doctors to discover,Who was the first person infected with HIV and how were they infected,science news,medical news
Timothy Ray Brown (1966) is an American boy considered to be the first person cured of HIV/AIDS.Brown was diagnosed with HIV in 1995 while studying in Berlin, Germany.they give him the nickname The Berlin Patient.
In 2007, Brown, who was dettect as HIV positive, underwent a
treatment known as hematopoietic stem cell transplantation to treat leukemia
disease.From matching sixty
donors,berlin doctors selected a [CCR5]-Δ32 homozygous individual with two
genetic copies of a rare variant of a cell surface receptor. This genetic trait
confers resistance to HIV infection by blocking attachment of HIV to the cell.
Roughly 10% of people of European ancestry have this inherited mutation, but it
is rarer in other populations.The transplant was repeated a year later after a
relapse. Over three years after the initial transplant and despite
discontinuing antiretroviral therapy, researchers detect there is no HIV in the transplant
recipient's blood or in various biopsies. the Levels of HIV-specific antibodies
have also decreased, leading to speculation that the patient may have been
functionally cured of HIV. However, scientists emphasise that this is an
unusual case that doesn't happen all time. Potentially fatal transplant complications
mean that the procedure could not be performed in others with HIV, even if
sufficient numbers of suitable donors were found.
However There is now doubt
that Timothy Brown's apparent cure was due to the unusual nature of the
stem cells that he received. As allready mentioned, he suffered
graft-versus-host disease. Six more people seem (as of 2017) to have been freed
of HIV after getting treament for graft-versus-host disease, and only one of
them had received CCR5 mutant stem cells. So it appears that when someone gets
graft-versus-host disease the transplanted cells may kill off all the host's
HIV-infected immune cells.
This is the great invetion of medical science against HIV
virus.
https://neptalks.blogspot.com/
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